TOP  > Personal Info.

Researcher DataBase - Personal Information : HIRAKAWA Kazutaka

HIRAKAWA Kazutaka
Professor
College of Engineering - Division of Applied Chemistry and Biochemical Engineering
Faculty of Engineering - Department of Applied Chemistry and Biochemical Engineering Graduate School of Integrated Science and Technology Department of Engineering - Applied Chemistry and Biochemical Engineering Course
Graduate School of Science and Technology,Research Division - Research of Nanomaterials Graduate School of Medical Photonics


image-profile
Last updated : 2024/11/07 2:05:08

Basic information on teaching staff

【Degrees earned】
The University of Tokyo   2000/3
 The University of Tokyo   1997/3
【Research Keyword】
Photochemistry, Photosensitized reaction, Porphyrin, DNA, Protein, Electron transfer, Photocatalyst, Reactive Oxygen, Metal nanoparticle
【Academic societies you belong to】
・American Chemical Society
・Society of Porphyrins and Phthalocyanines
【Research Seeds】
[1]. 新規光化学的がん治療薬の開発 ( 2019(FY) - ) [Category] 5. バイオ・ライフサイエンス [URL]
[2]. 1.低侵襲ながん選択的光線治療薬の開発/2.活性酸素の検出・評価法の開発 ( 2019(FY) - ) [Category] 7.地域連携 [URL]
 

Research information

【Papers, etc.】
[1]. Enhancement of fluorescence and singlet oxygen production of berberine on clay Nanosheets by surface-fixation Induced emission (S-FIE)
Journal of Photochemistry and Photobiology A: Chemistry 459/ - 116039 (2025) [Refereed] refereed [Internationally co-authored papers] non-internationally co-authored paper
[Lead author or co-author] co-author
[Author] Hakan Mori, Makiko Yamashina, Tamao Ishida, Masbooth Rasa Melechalil, Kazutaka Hirakawa, Shinsuke Takagi [DOI]
[2]. Photochemical protein damaging activity of tetrakis(p-allyloxyphenyl)porphyrin P(V) complexes
Photomedicine and Photobiology 45/ 29-33 (2024) [Refereed] refereed [Internationally co-authored papers] non-internationally co-authored paper
[Lead author or co-author] author
[Author] Kazuho Fukaya, Shigetoshi Okazaki, Hideki Kawai, and Kazutaka Hirakawa
[3]. Evaluation of the photosensitizer activity of hydrophobic phosphorus(V) porphyrins using the absorption spectral change of 1-benzyl-1,4- dihydronicotinamide
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 308/ - 123765 (2024) [Refereed] refereed [Internationally co-authored papers] non-internationally co-authored paper
[Lead author or co-author] author
[Author] Hiroko Hasegawa and Kazutaka Hirakawa [DOI]
[4]. Fluorination of tetraphenylporphyrin zinc complex enhances the protein photodamaging activity through electron transfer mechanism
Photomedicine and Photobiology 43/44/ 45-50 (2023) [Refereed] refereed [Internationally co-authored papers] non-internationally co-authored paper
[Lead author or co-author] author
[Author] Kazutaka Hirakawa, Satoki Matsui, Shigetoshi Okazaki [Notes] 全般
[5]. Protein Photodamaging Activity and Photocytotoxic Effect of an Axial-Connecting Phosphorus(V)porphyrin Trimer
Chemical Research in Toxicology 36/10 1623-1630 (2023) [Refereed] refereed [Internationally co-authored papers] non-internationally co-authored paper
[Lead author or co-author] author
[Author] Kazutaka Hirakawa, Naoki Kishimoto, Yoshinobu Nishimura, Yuko Ibuki, Masaaki Fuki, Shigetoshi Okazaki [Notes] 全般を担当 表紙掲載
[DOI]
【Books, etc.】
[1].
GAKUJUTSU TOSHO SHUPPAN-SHA CO., LTD. (2021)
[Book type]book(educational)
[Sole author, co-author, or author and editor] contributor
[Author]生駒修二、植田一正、梅本宏信、野口良史、平川和貴、宮林恵子、山田眞吉(五十音順) [REP page number] 34~43ページ
[2]. Photodynamic Therapy-from Basic Science to Clinical Research
Intech Open (2020)
[Book type]book(research)
[Sole author, co-author, or author and editor] contributor
[Author]Kazutaka Hirakawa [Range] Electron transfer-supported photodynamic therapy [Total page number] 229 [REP page number] 1-25 (Chapter 1)
[3].
Gakujutsu Tosho Shuppan-sha Co.,Ltd. (2020)
[Book type]book(educational)
[Sole author, co-author, or author and editor] contributor
[Author]生駒修二、植田一正、梅本宏信、野口良史、平川和貴、宮林恵子、山田眞吉(五十音順) [Total page number] 77 [REP page number] 34-42
[4]. Human Serum Albumin: Structure, Binding and Activity
Nova Science Publishers (2019)
[Book type]book(research)
[Sole author, co-author, or author and editor] contributor
[Author]Sabina Galiniak; (David Aebisher; Kazutaka Hirakawa; Dorota Bartusik-Aebisher; [Range] Evaluation of Photodynamic Agent Activity Using Human Serum Albumin [Total page number] 120 [REP page number] Chapter 3(33ページ分)
[5]. Reactive Oxygen Species (ROS) in Living Cells
IntechOpen (2018)
[Book type]book(research)
[Sole author, co-author, or author and editor] contributor
[Author]平川 和貴,Filip Cristiana,Abdurrahim Kocyigit,Nina Filip,Hui Xu$Teppei Takeshima$Patricia Siques$Chanchai Boonla$Giulia Guerriero [Range] Biomolecules Oxidation by Hydrogen Peroxide and Singlet Oxygen [REP page number] Chapter 9
[Notes] Chapter 9の全て
【Works】
[1]. Controlled Photodynamic Action of Axial Fluorinated DiethoxyP(V)tetrakis(p-methoxyphenyl)porphyrin through Self-Aggregation (2019/8 ) [Author] kazutaka Hirakawa [Category] the others [Details] Photodynamic action (photosensitized protein-damaging activity) of P(V) porphyrins can be controlled through self-aggregation and interaction with protein. [Place] Chemical Research in Toxicology, 2019 Volume 32, Issue 8 [URL]
[2]. Front Cover: Kinetics of Spontaneous Bimetallization between Silver and Noble Metal Nanoparticles (2018/8 ) [Author] kazutaka Hirakawa [Category] the others [Details] Silver‐core bimetallic nanoparticles form spontaneously from a physical mixture of polymer‐protected silver nanoparticles and other noble metal nanoparticles, for example platinum, rhodium, and palladium. An electron transfer reaction from Ag to other metal nanoparticles was proposed as the initial interaction between these metal nanoparticles. In general, parent Ag nanoparticles are relatively large compared with the other metal nanoparticles. This interaction results in the formation of small Ag‐core particles covered by mixed metal atoms. [Place] Chemistry An Asian Journal 13/15 [URL]
【Academic conference/research presentations】
[1]. ピリジンまたはピラジンを配位子にもつP(V)ポルフィリンの光増感剤特性におけるpHおよび溶媒効果
第46回日本光医学・光生物学会 (2024/7/6) other
[Presenter]平岩侑馬, 岡崎茂俊, 平川和貴
[Notes] 開催場所:浜松 主催団体:日本光医学・光生物学会
[2]. キノリン結合P(V)ポルフィリン光増感剤の活性制御と細胞毒性
第33回日本光線力学学会学術講演会(Laser Week IV in Tokyo) (2023/11/25) invited
[Presenter]平川和貴
[Notes] 開催場所:京王プラザホテル(新宿区) 主催団体:一般社団法人日本光線力学学会、特定非営利活動法人日本レーザー医学会
[3]. 銀および金/白金ナノ粒子の自発的複合化過程における表面プラズモン吸収の消失
第54回 中部化学関係学協会支部連合秋季大会 (2023/11/11) other
[Presenter]宮田峻佑,平川和貴
[Notes] 開催場所:三重大学、津市 主催団体:日本化学会
[4]. 天然色素ベルベリンの光励起状態高速緩和における立体構造の効果
第54回 中部化学関係学協会支部連合秋季大会 (2023/11/11) other
[Presenter]松浦統士, 平川和貴
[Notes] 開催場所:三重大学、津市 主催団体:日本化学会
[5]. キノリン結合P(V)ポルフィリン光増感剤のpHに依存する分子内電子移動および自己会合による活性制御
2023年光化学討論会 (2023/9/7) other
[Presenter]平川和貴, 山岡慎弥, 岡崎茂俊
[Notes] 開催場所:広島国際会議場、主催団体:光化学協会
【Joint or funded research】
[1]. funded (public)
( 2003/7 ~ 2004/3 )
[2]. joint (international)
leader ( )
【Grants-in-aid for Scientific Research
[1]. 自己会合と分子内電子移動の二重スイッチを利用するがん選択的光増感剤の開発 ( 2024/4 ~ 2027/3 ) Grant-in-Aid for Scientific Research (C) leader
[2]. 電子移動制御に基づく長波長応答性がん選択的光増感剤の創成 ( 2017/4 ~ 2020/3 ) Grant-in-Aid for Scientific Research (B) leader

[3]. 光増感剤修飾分子を用いたPCIの分子科学 ( 2014/4 ~ 2016/3 ) Grant-in-Aid for Scientific Research on Innovative Areas (B) member
[Notes] 連携研究者として参画、研究代表者:大槻高史教授(岡山大学)

[4]. 光増感によるエンドソーム脱出の分子科学 ( 2012/4 ~ 2014/3 ) Grant-in-Aid for Scientific Research on Innovative Areas (B) member
[Notes] 連携研究者として参画、研究代表者:大槻高史教授(岡山大学)

[5]. 電子移動で活性酸素機構を補完するがん光治療用ポルフィリンの開発 ( 2011/4 ) Grant-in-Aid for Young Scientists (B) leader

【Research Grants & Projects(except for KAKENHI)】
[1]. 希少金属の有効利用を志向した貴金属ナノ粒子の自発的複合化現象の解明と応用 (2022/4 - 2023/3 ) [Offer orgnization] 公益財団法人スズキ財団 [System name] 2021年度科学技術研究(一般) [Role] principal investigator
[2]. がん選択的低侵襲光治療薬の開発 (2021/4 - 2022/3 ) [Offer orgnization] 公益財団法人高橋産業経済研究財団 [System name] 令和3年度助成金(一般公募) [Role] principal investigator
[3]. 分光学的手法によるがん光治療薬の作用機序解明 (2020/7 - 2021/3 ) [Offer orgnization] 国立大学法人神戸大学 [System name] 令和二年度神戸大学分子フォトサイエンス研究センター共同利用研究 [Role] principal investigator
[4]. 電子移動に基づくがん細胞選択的光線治療薬の創成 (2020/4 - 2021/3 ) [Offer orgnization] 公益財団法人双葉電子記念財団 [System name] 自然科学研究助成 [Role] principal investigator
[5]. 分光学的手法によるがん光治療薬の作用機序解明 (2019/7 - 2020/3 ) [Offer orgnization] 神戸大学分子フォトサイエンス研究センター [System name] 共同利用研究 [Role] principal investigator
【Awards & Honors】
[1]. (2020/11)
[2]. (2016/4)
[3]. (2010/3)
[Association] Shizuoka University
[4]. (2009/7)
[Association] Japanese Society for Photomedicine and Photobiology
[5]. (2007/6)
[Association] The Chemical Society of Japan
【Patents, etc.】
[1]. リンポルフィリン化合物及びその製造方法、並びに生体分子損傷剤 [Application Number] 特願2020-141012 (2020/8/24)
[2]. The Phosphorus Porphyrin Compound, method for Producing Same, and Biomolecule Damaging Agent [Application Number] WO 2015/170562 A1 (2016/11/12) [Patent Number] WO 2015/170562 A1
[Notes] 国際公開番号 WO 2015/170562 A1(上記国際公開日)
[3]. リンポルフィリン化合物及びその製造方法、並びに生体分子損傷剤 [Application Number] 特願2016-517852 (2015/4/16) [Patent Number] 特許第6469096号 (2019/1/25)
[4]. (PCT出願)リンポルフィリン化合物及びその製造方法、並びに生体分子損傷剤 [Application Number] PCT/JP2015/061717 (2015/4/16)
[5]. リンポルフィリン化合物及びその製造方法、並びに生体分子損傷剤 [Application Number] 特願2014-097016 (2014/5/8)
【Holding academic or research conferences, etc.】
[1]. The 2020 International Chemical Congress of Pacific Basin Societies (2021/12)
[Role at conference, etc.] other [Site of conference, etc.] ハワイ州(アメリカ合衆国)
[Notes] シンポジウムオーガナイザー、2021年に1年延期
[2]. The 2020 International Chemical Congress of Pacific Basin Societies (2020/12)
[Role at conference, etc.] other [Site of conference, etc.] ハワイ州(アメリカ合衆国)
[Notes] シンポジウムオーガナイザー、2021年に1年延期
[3]. フォトダイナミックセラノスティクス研究会 (2017/1)
[Role at conference, etc.] is leader [Site of conference, etc.] 静岡大学浜松キャンパス
[4]. 第36回光化学若手の会 (2015/6)
[Role at conference, etc.] is leader [Site of conference, etc.] 静岡大学浜松キャンパス(第一部)、浜名湖ロイヤルホテル(第二部)
【Other academic research activity】
[1]. 日本レーザー医学会誌編集委員(学術誌の編集) (2022/4 - 2022/3 )
[2]. 日本レーザー医学会誌編集委員(学術誌の編集) (2020/12 - 2021/3 )
[3]. 日本レーザー医学会誌編集委員(学術誌の編集) (2019/4 - 2020/3 )
[4]. 日本レーザー医学会誌編集委員(学術誌の編集) (2018/12 - 2019/3 )
[5]. 学術誌の編集(International Journal of Photoenergy) (2014/4 )

Education related information

【Courses being taught this academic year】
[1]. Graduate School Course(Doctoral) 光量子分子科学 (2024(FY) - first semester )
【Number of students advising】
2023(FY)
Number of undergraduate students(junior students) 0
Number of undergraduate students(senior students) 3
Number of master's course students : 6
Number of doctorate course students (main advisor) : 1 Number of doctorate course students (assistant advisor) : 3
2022(FY)
Number of undergraduate students(junior students) 3
Number of undergraduate students(senior students) 3
Number of master's course students : 5
Number of doctorate course students (main advisor) : 1 Number of doctorate course students (assistant advisor) : 1
2021(FY)
Number of undergraduate students(junior students) 3
Number of undergraduate students(senior students) 3
Number of master's course students : 6
Number of doctorate course students (main advisor) : 1 Number of doctorate course students (assistant advisor) : 2
2020(FY)
Number of undergraduate students(junior students) 3
Number of undergraduate students(senior students) 3
Number of master's course students : 6
Number of doctorate course students (main advisor) : 1 Number of doctorate course students (assistant advisor) : 2
2019(FY)
Number of undergraduate students(junior students) 3
Number of undergraduate students(senior students) 4
Number of master's course students : 5
Number of doctorate course students (main advisor) : 1 Number of doctorate course students (assistant advisor) : 2
[Notes] 博士課程1名休学中
【Prizes students you are advising won】
[1]. ベストライティング賞、省エネルギー賞 (2017/9)
[Name of organization that offered the prize] 化学工学会
[Notes] 所属:総合科学技術研究科 化学工学会第49回秋季大会第16回プロセスデザイン学生コンテスト
[2]. 優秀ポスター賞 (2015/6)
[Name of student who received the prize] 南堀雅志
[Name of organization that offered the prize] 光化学若手の会
[3]. シーズ&ニーズビジネスマッチング研究発表会最優秀ポスター賞 (2014/12)
[Name of student who received the prize] 長谷川仁子
[Name of organization that offered the prize] 静岡県中小企業団体中央会、静岡県食品技術研究会
[4]. Poster Presentation Award (2013/11)
[Name of student who received the prize] 欧陽東彦
[Name of organization that offered the prize] 静岡健康・長寿学術フォーラム
[5]. Poster Presentation Award (2011/4)
[Name of student who received the prize] 井上思織
[Name of organization that offered the prize] Shizuoka Forum on Health and Longevity
【Information education-related information.】
[1]. X線業務従事者教育訓練(法令) (2020/4 )
[Notes] オンライン
[2]. X線業務従事者教育訓練(法令) (2018/4 )
[3]. X線業務従事者教育訓練(法令) (2017/4 )
[4]. X線業務従事者教育訓練(法令) (2016/4 )
[5]. X線業務従事者教育訓練(法令) (2015/4 )

Contributions to society

【Seminar,Workshop, Event, etc.】
[1]. extramural lecture 令和5年度 ふじのくに地域・大学コンソーシアム 共同授業 (2023/10 - 2023/10 )
[Details] 講師
[Notes] 静岡文化芸術大学
[2]. extramural lecture 第46回日本光医学・光生物学会の主催 (2023/4 - 2024/7 )
[Details] 学会の主催
[Notes] 本学浜松キャンパス
[3]. lecture meeting 演題:光でがんを治す「光増感剤で低侵襲にがんをやっつける」 (2016/10 - 2016/9 )
[Details] 静岡商工会議所・静岡大学工学部・浜松科学技術研究振興会交流会
[Notes] 静岡大学浜松キャンパス
[4]. extramural lecture 静岡大学・中日新聞連携講座 (2015/2 )
[Details] 光でがんに勝つ!
[5]. training courses 富士山麓医用機器開発エンジニア養成プログラム講師 (2013/10 - 2014/3 )
[Details] 光線力学的療法の原理と医療機器開発
[Notes] 沼津工業高等専門学校
【News coverage】
[1]. newspaper 光使ったがん治療実用化へ情報交換 (2017/1/24)
[Summary]主催したシンポジウムの新聞報道
[Notes] 静岡新聞
[2]. newspaper 静岡大学、がん光線力学療法向け化合物−深部細胞に効果 (2015/12/8)
[Notes] 日刊工業新聞
[3]. newspaper 新たな光増感剤開発-がん治療効果向上に期待― (2015/11/27)
[Notes] 中日新聞
[4]. newspaper がん治療の化合物開発 静大、酸素ない細胞にも効果 (2015/11/27)
[Notes] 静岡新聞朝刊29面、中日新聞朝刊9面
[5]. radio FM Hi! 静大スタイル (2015/7/9)
[Summary]研究紹介等
【Committees outside the university, etc.】
[1]. 日本レーザー医学会誌編集委員 (2023/4 ) [Association] 特定非営利活動法人日本レーザー医学会
[Details of activities]学術誌の編集者(Editor)
[2]. 日本光線力学学会理事 (2022/11 - 2024/3 ) [Association] 一般社団法人日本光線力学学会
[Notes] 学会運営
[3]. ふじのくに地域・大学コンソーシアム西部地域連携事業実施委員会 (2022/4 - 2023/3 )
[4]. 常任幹事 (2022/3 - 2024/3 ) [Association] 日本化学会東海支部
[5]. 日本光医学・光生物学会 理事 (2020/4 - 2021/3 ) [Association] 日本光医学・光生物学会
[Details of activities]学会運営
【Other social activities】
[1]. 放射線測定と評価 (2011/4 )
[Notes] 活動内容(福島第一原子力発電所事故に伴う放射能汚染の評価を福島市内で実施)
[2]. 学会賞審査委員 (2011/4 )
[Notes] 活動内容(日本光医学・光生物学会奨励賞の審査)
[3]. 地域支援(光抗菌技術の開発) (2011/4 )
[Notes] 支援先(アルケア株式会社)
[4]. 地域支援(食品用放射線計測法の開発) (2011/4 )
[Notes] 支援先(ディスクテック株式会社)
[5]. 技術相談:食品の放射能汚染評価法 (2010/4 )
[Notes] 活動内容(福島第一原子力発電所事故に伴う食品の放射能汚染評価法の相談と技術指導。)

International contributions

【Other international contributions】
[1]. International Conference on Artificial Photosynthesis-2024(国際会議プログラム委員) (2023/10 - 2024/7 )
[Notes] 国際学会のプログラム編集、招待講演の決定等
[2]. Journal of Photochemistry and Photobiology C: Photochemistry Reviews Associate Editor (2022/6 )
[3]. 国際会議シンポジウムオーガナイザー (2020/1 - 2020/12 )
[Notes] 環太平洋国際化学会議

Others

【School dean, etc.】
[1]. 工学部化学バイオ工学科長 (2018/4 - 2019/3 )